GRADUATE CURRICULUM FOR BIOLOGICAL INFORMATION SPECIALISTS: A KEY TO INTEGRATION OF SCALE IN BIOLOGY


Tracing genomic instability in induced mesenchymal stromal cell manufacture: an integration-free transfection approach

Abstract Here we systematically investigated genomic alterations from the initiation of induced pluripotent stem (iPS) cell generation to induced mesenchymal stromal/stem cell differentiation.We observed a total of ten copy number alterations (CNAs) and five single-nucleotide variations (SNVs) during the phases of reprogramming, differentiation and

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Harnessing case isolation and ring vaccination to control Ebola.

As a devastating Ebola outbreak in West Africa continues, non-pharmaceutical control measures including contact tracing, quarantine, and case isolation are being implemented.In addition, public health agencies are scaling up efforts to test and deploy candidate vaccines.Given the experimental nature and limited initial supplies of vaccines, a mass

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